question from a user

What's your experience with enclo alongside trt. Large chain in my area offers enclo but not hcg. Possible to maintain fertility on this protocol? Is enclo typically more effective with less frequent dosing?

AlphaMD's Answer


There are zero studies to cite where enclomiphene is used concurrently with TRT. For this reason, its use is still considered experimental. We have seen some men still maintain a measurable LH level with enclomiphene while on TRT, which would suggest it works. That being said, some men naturally can maintain LH release despite TRT use, even without enclomiphene.

Basically, if you ever choose to use enclomiphene as a substitute for hCG, you are choosing to be a test subject in an untested and unproven experiment.

hCG is proven to work and overcomes all suppressive effects of TRT. You have only seen clinics using SERMs along with TRT since new pharmacy regulations have made hCG hard to source. Basically, if you can get hCG, you should.

Related Questions

What's your experience with enclo alongside trt. Large chain in my area offers enclo but not hcg. Possible to maintain fertility on this protocol? Is ...

There are zero studies to cite where enclomiphene is used concurrently with TRT. For this reason, its use is still considered experimental. We have seen some men still maintain a measurable LH level ... See Full Answer

I started trt few months back and been prescribed Enclomiphene 25mg twice weekly. I was wondering if I added HCG to that protocol to help keep fertili...

Are you saying that you're on Testosterone injections & Enclomiphene at the same time? Either way, we would suggest that if you're trying to have a child now or within the next 6 months that HCG would... See Full Answer

Would you say that TRT with hCG is a much better option for someone that wants to maintain fertility as opposed to Enclomiphene mono therapy? I was co...

We would say that, yes. In general although Enclomiphene appears to have less side effects than Clomid, it has not been around as long as these other therapies and the long term effects are not 100% k... See Full Answer

Ready to get answers?
Ask your own question today.

Get $30 off your first month’s order

Enter your email address now to receive $30 off your first month’s cost, other discounts, and additional information about TRT.

Legal Disclaimer

This website is a repository of publicly available information and is not intended to form a physician-patient relationship with any individual. The content of this website is for informational purposes only. The information presented on this website is not intended to take the place of your personal physician's advice and is not intended to diagnose, treat, cure, or prevent any disease. Discuss this information with your own physician or healthcare provider to determine what is right for you. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. The information contained herein is presented in summary form only and intended to provide broad consumer understanding and knowledge. The information should not be considered complete and should not be used in place of a visit, phone or telemedicine call, consultation or advice of your physician or other healthcare provider. Only a qualified physician in your state can determine if you qualify for and should undertake treatment.