question from a user
If higher testosterone is causing changes to serotonergic pathways, could it be causing interactions with my SNRI medication?
AlphaMD's Answer
Testosterone increases serotonin signaling and is currently being studied as a treatment for depression.
As quoted in this article,
“The study has shown that testosterone increases the potential binding sites for commonly prescribed antidepressants such as SSRIs in the brain”
Basically testosterone makes medicines like SSRIs and SNRIs more effective, and may even mean patients can stop taking them once their testosterone levels become stable.
Related Questions
I’ve been thinking about how to have the conversation with my primary care doctor. I had a testicular torsion during my teenage years and would bet th...
It is true that TRT would not have any interaction with your current medications. The T levels you listed would be considered normal. Would even higher levels help with the medication induced drop in ... See Full Answer
Is there any reason to use Testosterone Cypionate and Enclomiphene concurrently?...
There are two negative feedback loops on LH release, estrogen and testosterone. So having normal or high levels of estrogen will shut down GnRH (gonadotropin releasing hormone) from the hypothalamus a... See Full Answer
Ready to get answers?
Ask your own question today.
Get $30 off your first month’s order
Enter your email address now to receive $30 off your first month’s cost, other discounts, and additional information about TRT.
Legal Disclaimer
This website is a repository of publicly available information and is not intended to form a physician-patient relationship with any individual. The content of this website is for informational purposes only. The information presented on this website is not intended to take the place of your personal physician's advice and is not intended to diagnose, treat, cure, or prevent any disease. Discuss this information with your own physician or healthcare provider to determine what is right for you. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. The information contained herein is presented in summary form only and intended to provide broad consumer understanding and knowledge. The information should not be considered complete and should not be used in place of a visit, phone or telemedicine call, consultation or advice of your physician or other healthcare provider. Only a qualified physician in your state can determine if you qualify for and should undertake treatment.