Check out this timeline we give to our patients: - The Start, Weeks 1-4 - Many notice effects from the first few injections. During this time, more benefits will become apparent as the half-lives... See Full Answer
For Testosterone, injections are much better than creams and gels. They are more consistent, potent, accurate, take less time investment, and generally cost way less. For a lot of people the idea of i... See Full Answer
While starting TRT would certainly increase your IGF-1, which would increase muscle mass over time, starting TRT is not always the answer. To be honest, it’s not clear that TRT would be the fix for yo... See Full Answer
At AlphaMD, we're here to help. Feel free to ask us any question you would like about TRT, medical weightloss, ED, or other topics related to men's health. Or take a moment to browse through our past questions.
So you’ve started TRT—or you’re thinking about it—and you’re ready to feel like your old self again. Great move. But did you know testosterone therapy can be even more effective when paired with certain adjunct therapies?
Think of TRT as your base camp. These add-ons? They’re like jet fuel for your goals—whether that’s better energy, improved body composition, or long-term hormonal balance.
Let’s break down the top adjunct therapies that can take your TRT to the next level.
TRT can reduce your body’s natural testosterone production—which sometimes means shrinking testicles or reduced fertility. HCG mimics luteinizing hormone (LH), stimulating your testes to stay active.
✅ Helps maintain testicular size
✅ Supports fertility
✅ Can boost mood and natural hormone balance
Testosterone can convert into estrogen (yes, men need some too!), but too much can cause water retention, mood swings, or gynecomastia (“man boobs”).
👉 Enter aromatase inhibitors like anastrozole. Used carefully, they can help manage estrogen levels and keep your hormones dialed in.
⚠️ Always work with a provider—over-suppressing estrogen can cause joint pain and fatigue.
Sermorelin is a peptide that signals your body to release more growth hormone (GH)—a powerful hormone involved in fat burning, muscle recovery, and better sleep.
🧬 Boosts recovery and lean muscle
🛌 Improves deep sleep quality
🔥 Supports fat loss and metabolism
It’s a great option if your GH levels are low or you’re looking to maximize your recovery from workouts or injuries.
Nandrolone (aka Deca) is an anabolic compound that can be prescribed in low doses as a TRT adjunct. It’s known for improving joint comfort, especially in aging men with chronic joint pain or inflammation.
💪 May help with muscle retention and strength
🪴 Improves collagen synthesis in joints
⚠️ Should only be used under medical supervision due to potential side effects
Anavar is an oral anabolic agent that’s relatively mild on the body and often used to support body recomposition. In clinical settings, it can help preserve muscle in men recovering from illness or weight loss.
🔥 Promotes lean muscle
⚡ May enhance strength and endurance
🧠 Can improve confidence and body image
Not for everyone—but under close medical oversight, it can be a powerful tool for targeted physique goals.
DHEA and pregnenolone are precursors to testosterone and other important hormones. Low levels can impact your mood, memory, and libido.
🌈 Supports brain function
❤️ Helps with emotional resilience
🔀 Can improve overall hormonal synergy with TRT
Even with great testosterone levels, low thyroid function can leave you tired, foggy, and sluggish.
🔽 Low Free T3 or elevated Reverse T3? TRT won’t fix that.
Some men benefit from thyroid support like T3/T4 combos to truly feel their best.
No surprise here—your habits still matter.
• Lift weights: TRT works best with resistance training
• Eat clean: Whole foods, healthy fats, key micronutrients
• Sleep deep: At least 7–8 hours for optimal recovery
• Manage stress: Chronic cortisol is a testosterone killer
Final Thoughts:
TRT can be a game-changer—but it’s just the start. With the right support (think: HCG, Sermorelin, Nandrolone, lifestyle upgrades), you can fully optimize your energy, strength, and well-being.
AlphaMD takes a personalized approach to hormone therapy—because one-size-fits-all never works when it comes to your health.
At AlphaMD, we're here to help. Feel free to ask us any question you would like about TRT, medical weightloss, ED, or other topics related to men's health. Or take a moment to browse through our past questions.
Check out this timeline we give to our patients: - The Start, Weeks 1-4 - Many notice effects from the first few injections. During this time, more benefits will become apparent as the half-lives... See Full Answer
For Testosterone, injections are much better than creams and gels. They are more consistent, potent, accurate, take less time investment, and generally cost way less. For a lot of people the idea of i... See Full Answer
While starting TRT would certainly increase your IGF-1, which would increase muscle mass over time, starting TRT is not always the answer. To be honest, it’s not clear that TRT would be the fix for yo... See Full Answer
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