Does Ostarine MK-2866 work? Can it replace Testosterone? SARM & TRT Discussion

Author: AlphaMD

In this video, we're going to be discussing Ostarine MK-2866, a SARM that is often considered to be a potential replacement for testosterone. We'll be looking at the evidence behind Ostarine MK-2866, as well as answering any questions you might have about it.

It should be noted again, despite the disclaimer in this video, that SARMs are not for human consumption nor regulated by the FDA. They cannot be prescribed & we cannot recommend them. This is for educational purposed.

Link to current Reddit AMA about this topic:


This editable transcript was computer generated and might contain errors. People can also change the text after it was created.

Garrett Soames:  Hey everybody. Today we're gonna be talking about Sarms. Again. Our first sarm is Austrian also known as Mk2866. I'm sure you guys have heard of Austrine. But to review Austrian is one of the original sarms. Again, a sarm is a selective androgen receptor modulator, As you know, these drugs still are not FDA approved. Their purpose was to hopefully supplant testosterone with fewer side effects.

Garrett Soames:  We're going to be discussing it along with other sarms basically to narrow down again. What is safe? What's not again? We are not promoting that the use of any of these. Psalms as again, they are not FDA approved but because we are getting so many questions about them, we do want to touch on them a little bit. So, Austrian is It like other sarms, it attaches to androgen receptors and essentially it does the same thing as testosterone. It triggers that are nitrogen, uptake and retention and muscles for muscle growth. It has like other sarms the potential to have more activity in muscle and bone than in other tissues, where we don't want as much androgen activity such as in the prostate.

Garrett Soames:  And it would seem that according to what studies limited studies. We have on Austrian, it does do that. It does attach with much more affinity to muscle and bone as opposed to prostate or male breast tissue. So it does seem to deliver in in that regard. Psalms were created with the goal in mind to reduce if affectation on the pituitary gland. It would seem that according to what studies have been done. It does actually. Suppress both LH and FSH from the pituitary gland. So Austrian did fail in that department.

Garrett Soames:  So, it does actually. Ultimately reduce your natural production of testosterone. By affecting the pituitary gland. So keep that in mind. A lot of people are asking questions. Well, can I add something like Austrian or whatever to my TRT to get better effects?

Garrett Soames:  In reality, it does not seem to be the case as it does still affect pituitary gland. In general, if, if there were any benefit to adding something like Austrian to your TRT regimen, it would be that it would likely be taking up some more of the sex hormone binding globulin. Um, making more of the testosterone that you're you're supplementing with more effective. Austrian is typically taken like other sarms. It's an oral medication dosing. Again, cannot be clearly defined at this point because we have no actual literal human studies. So bear that in mind, these have never been officially

Garrett Soames:  Tested in a double-line study or anything in humans. But in animal studies, they have been proven to be safe at least in whatever studies they've been doing on that dosing in in adults, is typically done anywhere between five to upwards of sometimes, 30 milligrams, it's half life is 24 hours. So typically, it would be dose once daily and the higher. The dose goes generally, again, the more effect you would have The main reason why men are using Sarms these days. As they are, renowned to have better reduction in overall body fat than then TRT. Anecdotally. This this has been said over and over.

Garrett Soames:  It. So in men that are taking Austrian, they seem to at least they state that they're losing. Body fat and a significant rate. Um again these all have to be taken with the grain of salt. It's important to remember as well that because these aren't FDA regulated. These are literally all made in someone's basement. These are not illegal but only because they are written with the express instructions that these are not to be used in humans. So this is not for human consumption. That is the only reason these are legal and able to be purchased online. And it's the only reason the FDA has not come and and made a bunch of arrests for these. So I want to be very clear. We're not recommending their use

Garrett Soames:  Um, but because we get so many questions we do want people to at least be knowledgeable about it. Ultimately, we do not recommend you, add it to your TRT. There is no additional benefit traditionally TRT alone. Can give you all the benefits you need. And according to the only human study, there's only one. Only one human study on Sarm so far, three quarters of the people who took it in the phase one of that trial had to quit because of side effects. One thing to remember, one of the reasons we stopped making testosterone pills is because they were very harsh on the liver. And lo and behold the sarms have been proven so far to be also very harsh on the liver, causing elevation and liver enzymes, elevation and bilirubin.

Garrett Soames:  With that, in mind, we cannot recommend that you take austering. As it has essentially been proven to be harmful to the liver. If you do choose to take it, it would obviously need to be cycled off to give your liver a chance to heal. other than that, Be safe again. This is Garrett with Alpha MD and feel free to message us if you have any other questions.

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