question from a user

Do you have a protocol for someone wanting to come off after a couple years?

AlphaMD's Answer


There is no "one answer fits all" to this question, as so much about starting TRT as well as coming off of a medication, has to do with the individual's goals of care. Analyzing each patient's regimen, dosage, and goals of care, an experienced provider will work with each individual patient to create a care plan that addresses both the initiation of medication and the cessation of it.

That said, most men would benefit from pharmaceutical assistance in reactivating their HPTA axis through use of one or more medicines. hCG and a SERM like enclomiphene are commonly used. Typically a tapered dosing protocol is used, often over 6 or more weeks. hCG is typically used before cessation of TRT, while the SERM is used after.

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